In this pixel art rendition I replaced the the characters of Super Mario Bros. for female characters becoming Super Maria Sis. in the tittle.
Mario became Maria just because it’s a single letter change and it works well. Marissa would also have worked.
Luigi became Ligia. Other candidates were Lucia and Luiza. In Italian the feminine name for Luigi is Luigina. Luigi is one of the many Italian forms for the german name Ludwig, which in French becomes Louis. So Luise would have been another candidate. In Portuguese Luís, Luis, or Luiz and their feminine version Luisa, Luíza. I choose Ligia because of the “G” sound.
It’s possible to create a patch over the original NES game to make this art become a real game. There is a lot of examples on how to do that on this article from Female-Characters NES ROM hacks.